Gastric acid secretion stimulated with intraduodenally administered histamine in rats
نویسندگان
چکیده
منابع مشابه
The effect of bromocriptine on basal and histamine-stimulated gastric acid secretion in anesthetized rats
Introduction: The protective and antisecretory effects of dopamine agonists on the stomach have been already reported, but the effect of bromocriptine (D2 dopamine agonist) on histamine stimulated gastric acid secretion (GAS) needs to be investigated. Methods: For gastric sampling, animals were anesthetized and a polyethylen tube was introduced into the stomach through esophagus. A cannula ...
متن کاملHistamine dependence of pentagastrin-stimulated gastric acid secretion in rats.
Does gastrin stimulate gastric acid secretion by direct action on oxyntic cells, by releasing histamine, or by being potentiated by histamine? Previous studies in the mouse pointed to gastrin-regulated histamine release. Guinea pig and rat are well known to vary in their sensitivity to histamine. Therefore, the effects of histamine and pentagastrin were compared quantitatively on isolated, lume...
متن کاملthe effect of bromocriptine on basal and histamine-stimulated gastric acid secretion in anesthetized rats
introduction: the protective and antisecretory effects of dopamine agonists on the stomach have been already reported, but the effect of bromocriptine (d2 dopamine agonist) on histamine stimulated gastric acid secretion (gas) needs to be investigated. methods: for gastric sampling, animals were anesthetized and a polyethylen tube was introduced into the stomach through esophagus. a cannula was ...
متن کاملEffect of Esophageal Distention on Basal and Stimulated Gastric Acid Secretion in Rats
It is well established that the esophageal distention (ED) leads to gastric relaxation, partly by vago-vagal reflex, but till now, the effect of ED on gastric acid secretion has not been investigated. The aim of this study was to investigate the effect of ED on basal and stimulated gastric acid secretion. Methods: Adult male Wistar rats (200-240 g) were deprived of food but not the water 24 h b...
متن کاملSodium hydrosulfide upregulates mRNA and protein expression of TGF-α in gastric mucosa in experimental model of stimulated gastric acid secretion in rats
Objective(s): Transforming growth factor alpha (TGF-α) has been shown to modulate the gastric acid secretion. Therefore, the aim of the present study was to investigate the effect of sodium hydrosulfide (NaHS) on TGF-α expression in gastric mucosa in rats. Materials and Methods: Eighteen rats were randomly divided into 3 groups (6 per group). To determine the effect of NaHS on gene and protein ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1989
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)56197-2